Yes, with PS3Hen. Makes it easy to play ISOs I download from the Repo (when I want to play them on a big screen instead of on the Vita/PSP). I have a PS1 and PS2 hooked up as well, yet lately I'm always playing my physical PS1 games on my PS3 as well...I guess it's cool to have nearly unlimited save data space.
I also still just really dig the PS3 XMB aesthetic. It still looks beautiful on modern TVs. Recently I also finally played the Ico/SoTC collection and Medal of Honor: Frontline remaster. Lots of PS3 gems out there I'm just now getting to.