Fields of Mistria if you like Stardew Valley. It has 80s anime aesthetic, a cool breeding mechanic for the animals and a very engaging main story, and the individual stories are also fun. If you want a 3D version with mermaids too, try Coral Island.
I'm also eyeing Welcome to Elderfield, which mixes the farm sim like Stardew Valley with the horror (and some RNG ) of Fear & Hunger.
Speaking of Fear & Hunger! If you want a very hard dungeon crawler, try Fear & Hunger and its sequel. The 3rd game is coming, apparently.
Void Stranger is my current pick. It has GB-like graphics and it is a very interesting puzzle game that you need to traverse an abyss to save someone, and that description is a disservice to a great plot with many twists and turns. You need to traverse rooms using a staff that removes blocks and places them back, creating a path. You also need to avoid monsters and some other obstacles and get to the deepest parts.
Vampire Therapist is a visual novel and it is exactly what it says in the tin, and it is amazing. Another visual novel that I very highly recommend is Slay the Princess. Both are incredible. This later is better going in blind.
Speaking of vampires, Cabaret is something I played the demo and is on my wishlist. You are a recently-awakened vampire and your decisions change your path, and you also have skill points that also give different options, but this one is more of a point-and click and not a VN.
Adventure/Point-and-click gamer? Lacuna, Kathy Rain, The Darkside Detective duology. Thibleweed Park was created by the minds behind Maniac Mansion.Wait, do you want 3D? Alfred Hitchcock's Vertigo is a good pick if you miss the Telltale games. Gray Matter was made by the creator of Gabriel Knight and while it misses the mark in some areas, it is solid.
King's Field and other dungeon-crawling? Lunacid is very good (from the creator of Lost in Vivo), Monomyth is also highly recommended. If you want something unique, try Cryptmaster, which mixes dungeon crawler and...typing.
Do you like Darkest Dungeon? There's the sequel, and there is also Iratus: Lord of the Dead, which is the polar opposite: you are the necromancer getting body parts and climbing out of the dungeon to enact your revenge and turn the entire world into a place of the undead.