Not really. The lock-on gimmick was cool don't get me wrong, but it required a minimum of two games to be programmed exactly the same and with the lock-on in mind to be effective. For example, if Fatal Fury 2 had been a lock-on game with Art of Fighting, that would allow for characters from both games to fight one another as the two games were programmed specifically to do so. But plonking Super Street Fighter II to Fatal Fury 2 would result in an error as the two were not designed to "combine" in such a way. Much like plonking Castlevania: Bloodlines into Sonic & Knuckles.
In the end, S&K worked as a fantastic marketing gimmick, but had exceedingly limited commercial viability otherwise - it required developers/publishers being willing to spend extra to make & people to be willing to buy two or more similar games for the sole purpose of combining them Devastator-style.
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