Interesting uses of sound and audio in video games

[Turbo Kid]

This isn't just another "cool music" or "great sound design!" or "awesome voice acting!" thread. I'm talking about games that use audio in clever ways.

The Mario games have a lot of cool little audio cues I'd like to mention as well like when you kill 8 enemies in a row with each kill triggering a slightly different sound before you eventually get a 1-up.

Listen to the musical shift when he goes in and out of water. Cool audio cues in the labyrinth too.

 

[Segadude113]

Wario Land 4 on GBA and Tempo for Sega 32X having full vocals in their songs was pretty mindblowing.

 

[bjork]

There's a series of sound-based mazes in The Witness that require you to listen to birds chirping to determine if it's a high/mid/low pitch, which you then use to draw the line through the maze. Later on in the game at the sunken ship, there's a maze that employs multiple requirements and for the sound one, the birds are replaced with sounds of ship settling - it is without a doubt the hardest puzzle I've ever tried in a game, even seeing the solution and having it explained, it still doesn't seem right.

The bit generation games on GBA all did different stuff with sound iirc and I want to say there was one you could play solely by listening and not looking at it? It's fuzzy in my memory.