90% of the time I use a controller. I used to use mouse & keyboard a lot more, but I have carpal tunnel in both my wrists and M&K tends to make my hands go numb now. Boo. The only time I use M&K are in FPS games that I learned to play on it (like Valve games) or FPS games that don't have particularly good (if any) controller support. Mostly old games in that case (System Shock 2, my love). I'll also use M&K for RTS and MOBA games, though I don't play much of those genres. Overall, I'd love to use M&K more, but I just don't have a good time when my hands are numb and/or feel like they're on fire. x)