Leaving all the food puns and jokes aside for a moment... if you never had any experience at all with nuzlockes and such I'd say the experience can be somewhat harrowing. If I were you'd select to do so with a game in the franchise with which you have a decent level of understanding already, so that your knowledge will easy transfer and allow you to have a somewhat smoother experience.
Failing that, maybe work with a more flexible ruleset, for starters, even if violates the normal nuzlocke precepts, at first.
Failing that, maybe work with a more flexible ruleset, for starters, even if violates the normal nuzlocke precepts, at first.