I used to play using RetroArch early on before DuckStation was a thing, one reason I prefer RA over ePSXe is just less hassle with plugin that setting up and tweaking a miserable experience at the time. Then someone/a YouTube channel mention DuckStation for its simple UI, and performance (including enhancement) that is almost a damn witchcraft making it better than ePSXe/RA in every aspect.
At this same time, PCSX2 also got massive overhaul using the same foundation as DuckStation that also significantly improve the performance, but that's story for another time.
Couple years later, when I took interest in Princess Crown (while the English patch is in limbo) and Baroque ~Yuganda Mousou~ (after playing the PS1 version), 2 out of 3 Sega Saturn core simply doesn't work on my end to run both, and the one that is work just finnicky to setup (control, hotkey, and whatnot). I gave up at that point. At first I look for the MednafenGUI but those has horrendous UI with not-so-good setting, in the end I rawdog OG Mednafen instead. It's actually work better and easier to setup despite having no UI.
So yeah, my experience with RA has been mixed, and since then, I never look at RA again. Even on my phone to play Chrono Trigger I just use whatever SNES emulator that available (Snes9x EX+). Also, recording footage on RA is not a nice either since the hotkey overlap with my OBS hotkey, and I can't be bother to change everything.
Maybe I would "love" it if I were to install it on my PS4 or XS (if I have one), but since I have PC, there's no reason for me to install on that system.